By now, most of you know that the artificial sweeteners are harmful to your health. But, many of you don’t know that the FDA knows this, too.
And they’ve known about it for decades.
They have known this from the start!
In 2005, a FDA document came out concerning the health dangers of using sucralose (Splenda®). FDA Rules and Regulations Federal Register Report Vol. 63, No. 64, 16426 is found in my book Splenda: Is It Safe Or Not?.
The manufacturer of Splenda, McNeil Nutritionals stated back in 2005:
. . the FDA’s Final Rule makes clear that many of these findings, such as cecal enlargement, are not the toxic effects of sucralose, but rather a normal physiological adaptation to poorly absorbed dietary components such as sucralose.”
To me, this statement confirms that your kidneys and intestines become inflamed when exposed to man-made chemicals that are altered in the lab to resist being properly absorbed.
Um hum, this means sucralose.
Humans Are Guinea Pigs
Based on their comprehensive review of the sucralose database, the FDA recommended that the rat be used as the most appropriate experimental model in the studies to establish a safe level of sucralose for human consumption.
I disagree with the use of lab rats for human safety testing because rats produce the antioxidant vitamin C in their livers, unlike humans who do NOT.
This is why the Guinea pig once was the primary lab animal used in experiments back in the day because, like humans, the Guinea pig does NOT produce this natural antioxidant in its liver.
All primates (including humans), the Guinea pig, and one type of bat in India don’t produce vitamin C in their livers. Just FYI.
According To The FDA ….
Using the no-observed-effect level of 500 mg/kg bw/d for sucralose and applying a 100-fold safety factor, the agency determined a safe ADI of 5 mg/kg bw/d for sucralose. The EDI for sucralose is 1.6 mg/kg bw/d.
This determination began in the FDA Rules and Regulations Federal Register Report Vol. 63, No. 64, 16426 and was based on the following study:
- In a 26-week study, sucralose was administered to 20 rats per sex per group by gavage at dosages of 0,750,1500, and 3000 mg/kg bw/d.
- Seven animal deaths occurred during the study that were attributed either to spontaneous causes not related to treatment, or technical trauma during dosing. Note: if seven lab animals die during any study, the cause should be determined and documented. These seven deaths were recorded as “unresolved.” To me, this invalidates this study right here.
- Water consumption was significantly increased in the sucralose-treated rats relative to the control rats, This is a significant point that went unnoticed.
- Cecal enlargement (part of the large intestine) was the only effect of sucralose noted that was dose-related among both sexes of the sucralose-gavaged rats. This wasn’t the only negative effect of the study, but it was an isolated effect that both genders had in common.
- Cecal enlargement was noted as a normal physiological adaptation to poorly absorbed dietary compounds. Again, this confirms the kidneys and intestines become inflamed when exposed to this particular man-made chemical that is altered to resist being properly absorbed.
- Relative kidney weight of the high-dose group was significantly increased; however, this was interpreted as not associated with toxicologically significant renal histopathology or diseased tissue. So if the kidney was not diseased, then it must be enlarged due to the presence of sucralose, right?
- Decreased body weight gain was observed in the sucralose-treated rats of the high-dose group.
A Second Study
The FDA Rules and Regulations Federal Register Report Vol. 63, No. 64, 16420, A1 Reproductive toxicity study states:
- During a Two-Generation reproductive toxicity study in rats (E056), significant decreases in relative thymic weights were noted in both male and female after dietary administration of sucralose at the high-dose (3%) level.
So now we have kidney stress AND thymus affects.
FDA Rules and Regulations Federal Register Report Vol. 63, No. 64, 16424, b. Immunotoxicity study in rats resulted in the following:
- As reported by McNeil and as noted in the agency’s review of the sucralose data, thymus, spleen, and hermatological changes were observed in rats at the high dose levels in some of the short-term and long-term sucralose feeding studies.
- The following effects were noted:
- Decreased thymus and spleen weights,
- Lymphocytopenia (this is when the lymphocyte count in your bloodstream is lower than normal).
- Cortical hypoplasia (incomplete development of outer layer) of the spleen and thymus.
McNeil stated that the effects were due to reduction in food consumption.
Do you believe that?
These studies and the FDA reviews clearly state that consumption of sucralose in rats result in adverse effects to the:
Why can’t these corporations and government agencies be honest with the consumer? And, so it continues today …..
Contact me and let’s talk if you want more information about the dangers of the artificial sweeteners.
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Disclaimer: This article is for informational purposes only, and is educational in nature. The FDA may not have evaluated some of the statements. This article is not intended to diagnose, treat, cure, or prevent any disease. Please discuss with your own, qualified health care provider before adding supplements or making any changes to your dietary program.
Before taking vitamins, consult your doctor; pre-existing medical conditions or medications you are taking can affect how your body responds to multivitamins.
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